• 杨召辉 (Zhaohui Yang)

    博士、研究人员
    硕士研究生导师
    Ph.D.Lecturer

    Email: yangzh@lpbr.cn

    一、受教育及工作经历 Education

    2005年7月-2009年7月,苏州大学生命科学学院,生物科学专业,获理学学士学位
    2009年8月-2014年12月,中科院昆明动物研究所,遗传学专业,获遗传学博士学位
    2015年01月-至今,昆明理工大学灵长类转化医学研究院,讲师
     

    2005.7-2009.7:Soochow University; Bachelor in Biology

    2009.9-2014.12:Kunming Institute of Zoology, Chinese Academy of Sciences; PhD in Genetics

    2015.1- present: Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology; Lecturer

    二、主要研究方向 Fields

    主要从事群体遗传学和比较基因组学研究,从遗传学角度探讨灵长类基因组的多样性以及东亚人群肤色的紫外适应性进化。

     

    My research focuses on population genetics and comparative genomics.

    (1) The adaptive evolution of East Asians skin color.

    (2) The diversity of primate genome.

    三、承担科研项目情况 Project List

    1. 、国家自然科学青年基金、31601016、高原藏族人群肤色适应性进化的分子机制研究、2017-2019、24万、在研、主持。
    2. 、云南省科技厅青年基金、2017FD092、紫外线调控色素基因OCA2表达以及对云贵高原人群表皮黑色素生成的影响、2017-2020、5万、在研、主持。
    3. 、云南省教育厅资助基金、2017ZZX140、南亚语系人群肤色变异的遗传学研究、2017-2019、4万、在研、主持。
    4. 、云南省级人培项目、KKSY201526061、色素基因OCA2功能及东亚人群肤色变浅分子机制初探、2015-2018、5万、结题、主持。
    5. 、遗传资源与进化国家重点实验室开放课题、GREKF15-06、藏族人群对高原强紫外辐射的适应性进化机制研究、2015-2018、12.25万、结题、主持。
    6. 、国家基金委重大研究计划、91631307、亚欧人群色素相关表型的进化与多基因作用机制、2017-2019、240万、在研、参与。
    1. The molecular mechanism of skin color adaptive evolution in high altitude Tibetan populations, (NO. 31601016), National Natural Science Funds (NSFC).
    2. Regulation of pigmentation gene OCA2 expression and its effect on melanogenesis in Yunnan-Guizhou Plateau Population, (NO. 2017FD092), Science and technology project of Yunnan Province.
    3. Genetics study on skin color diversity in Austro-Asiatic language Population, (NO. 2017ZZX140), the scientific research project of Yunnan Provincial Department of Education.
    4. Function study of pigmentation gene OCA2 and molecular mechanisms of Skin lightening in East Asian Population, (NO. KKSY201526061), the Personnel Training Project of Yunnan Province.

    四、获奖情况 Honors

    1. 2013 年度 保罗生物科技优秀学生奖
    2. 2014 年度 中国科学院朱李月华优秀博士生奖学金
    3. 2014 年度 博士研究生国家奖学金
    4. 2015 年度 中国科学院大学优秀毕业生
    5. 2017 年度 云南省优秀博士毕业论文
     
    1. Excellent Doctoral Dissertation Award of Yunnan Province in 2017
    2. Outstanding Graduates of Chinese Academy of Sciences in 2015
    3. National Scholarship in 2014
    4. Chu Yuet Wah Outstanding Doctoral Award in 2014
    5. Paul Biotechnology Outstanding Student Award in 2013

    五、代表性论文 Publication List

    1. Chu Chu*, Zhaohui Yang*, Jiayin Yang, Li Yan, Chenyang Si, Yu Kang, Zhenzhen Chen, Yongchang Chen, Weizhi Ji, Yuyu Niu#. (2019). Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases. BMC Biotechnology 19: 7. IF= 2.605.
    2. Zhaohui Yang*, Hong Shi*, Pengcheng Ma*, Shilei Zhao, Qinghong Kong, Tianhao Bian, Chao Gong, Qi Zhao, Yuan Liu, Xuebin Qi, Xiaoming Zhang, Yinglun Han, Jiewei Liu, Qingwei Li, Hua Chen#, Bing Su#. (2018). Darwinian Positive Selection on the Pleiotropic Effects of KITLG Explain Skin Pigmentation and Winter Temperature Adaptation in Eurasians. Molecular biology and evolution 35(9), 2272–2283. IF=10.217. (1 次引用)
    3. Zhaohui Yang*, Hua Zhong*, Jing Chen*, Xiaoming Zhang*, Hui Zhang, Xin Luo, Shuhua Xu, Hua Chen, Dongsheng Lu, Yinglun Han, Jinkun Li, Lijie Fu, Xuebin Qi, Yi Peng, Kun Xiang, Qiang Lin, Yan Guo, Ming Li, Xiangyu Cao, Yanfeng Zhang, Shiyu Liao, Yingmei Peng, Lin Zhang, Xiaosen Guo, Shanshan Dong, Fan Liang, Jun Wang, Andrew Willden, Hong Seang Aun, Bun Serey, Tuot Sovannary, Long Bunnath, Ham Samnom, Graeme Mardon, Qingwei Li, Anming Meng#, Hong Shi# & Bing Su#. (2016). A genetic mechanism for convergent skin lightening during recent human evolution. Molecular biology and evolution 33(5), 1177–1187. IF=10.217. (12 次引用)
    4. Xiaoming Zhang*, Xuebin Qi*, Zhaohui Yang*, Bun Serey, TuotSovannary, Long Bunnath, Hong SeangAun, Ham Samnom, Hui Zhang, Qiang Lin, Mannis van Oven, Hong Shi# & Bing Su#. (2013). Analysis of mitochondrial genome diversity identifies new and ancient maternal lineages in Cambodian aborigines. Nature Communications 4: 2599. IF=12.353. (18 次引用)
    5. Xuebin Qi*, Chaoying Cui*, Yi Peng*, Xiaoming Zhang*, Zhaohui Yang*, HuaZhong, Hui Zhang, Kun Xiang, Xiangyu Cao, Yi Wang, Ouzhuluobu, Basang, Ciwangsangbu, Bianba, Gonggalanzi, Tianyi Wu, Hua Chen, Hong Shi# and Bing Su#. (2013). Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the Tibetan plateau. Molecular biology and evolution 30(8), 1761-1778. IF=10.217. (82 次引用)
    6. Yi Peng*, Zhaohui Yang*, Hui Zhang*, Chaoying Cui*, Xuebin Qi, XiongjianLuo, Xiang Tao, Tianyi Wu, Ouzhuluobu, Basang, Ciwangsangbu, Danzengduojie, Hua Chen, Hong Shi# and Bing Su#. (2011). Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas. Molecular biology and evolution28 (2), 1075-1081. IF=10.217. (196次引用)
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