• 白冰(Bing Bai)

    博士、研究人员

    讲师

    Ph.D.Lecturer

    Email: baib@lpbr.cn

    一、受教育及工作经历Education and Academic Positions

    2000.09-2004.07; 云南大学,信息学院,计算机科学与技术,工学学士

    2004.09-2007.07;云南大学,信息学院,计算机软件与理论,理学硕士

    2008.01-2015.05;昆明学院,信息技术学院,讲师

    2011.09-2015.05;中国科学院昆明动物研究所;遗传学,理学博士

    2016.01-2019.12;云南省第一人民医院,博士后

    2020.03-至今;昆明理工大学灵长类转化医学院,讲师

     

    2000.09-2004.07; School of Information, Yunnan University, B.E. in Computer science and technology

    2004.09-2007.07;School of Information, Yunnan University,M.S. in Computer software and theory

    2008.01-2015.05;School of information technology, Kunming College, Lecturer

    2011.09-2015.05;

    2011.09-2015.05;Kunming Institute of Zoology, Chinese Academy of Science, PH.D in genetics

    2016.01-2019.12;First Hospital of Yunnan, Postdoc

    2020.03-Now;Lecturer, Institute of Primate Translational Medical,Kunming University of Science and Technology

    二、主要研究方向Research Interests

    1. 灵长类多组学数据库建构
    2. 发育障碍类疾病病因研究  
    1. Research of the cause of developmental disability
    2. Primate multi omics database construction

    三、研究领域描述 Research Field

    运用生物信息分析和群体遗传学理论分析导致儿童或非人灵长类发育障碍疾病发生的原因;分析灵长类遗传多样性,并整合其他组学数据,构建灵长类多组学数据库。

     

    Analyze the cause of developmental disability of children and non-primate species based on bioinformatics analysis and population genetics. Analyze genetic diversity and integrate data of other omics to construct primate multi omics database.

    四、承担科研项目情况 Research funding

    1. 中国博士后科学基金项目,面上资助项目,2016.11-2019.12,5万 ,主持
    2. 云南省卫生科技计划项目,项目名称:孤独症circRNA异常调控研究,2016.01-2018. 12 , 20万,主持
    3. 国家重点基础研究发展计划项目子课题,项目名称:家犬性状进化的遗传和基因组研究,2013.07-2017.08, 300万元,已结题,主要参与
    4. 国家自然科学基金委重大研究计划培育项目,项目名称:家犬在人工选择下的高原适应机制研究,2013.01-2015.12,80万,主要参与
    1. 2016.11-2019.12, National Postdoctoral Science Foundation of China, general project, PI
    2. 2016.01-2018.12, The research of abnormal regulation of circRNA in autism, Health Technology Commission of Yunnan Province,PI
    3. 2013.07-2017.08, Genetics and genome research of dog phenotype evolution, sub-project of Key Project of Chinese National Programs for Fundamental Research and Development, principle member.
    4. The research of high altitude adaption mechanism of dogs under artificial selection, Training Program of the Major Research Plan of the National Natural Science Foundation of China, principle member.

    五、代表性论文 Publication

    1. Bai,Bing ; Guo,Yi-ran; Zhang, Yin-Hong; Jin, Chan-Chan; Zhang,Jin-Man; Chang, Hong; Zhu, Bao-Sheng, Novel DOCK7 mutations in a Chinese patient with early infantile epileptic encephalopathy 23, Chinese medical Journal, 2019.3.5, 132(5): 600~603
    2. Guo Dong Wang(#) ; Xiu Juan Shao(#) ; Bing Bai(#) ; Junlong Wang; XiaoboWang; Xue Cao; Yan Hu Liu; Xuan Wang; Ting Ting Yin; Shao Jie Zhang; Yan Lu;Zechong Wang; Lu Wang; Wenming Zhao; Bing Zhang; Jue Ruan; Ya Ping Zhang, Structural variation during dog domestication: insights from gray wolf and dhole genomes , National Science Review, 2018.7.19, 6(1): 110~122
    3. Bai, Bing(#),Zhao, Wen-Ming(#),Tang, Bi-Xia(#),Wang, Yan-Qing,Wang Lu,Zhang, Zhang,Yang, He-Chuan,Liu, Yan-Hu,Zhu, Jun-Wei,Irwin, David M,Wang, Guo-Dong(*),Zhang, Ya-Ping(*),DoGSD: the dog and wolf genome SNPdatabase.,Nucleic Acids Res,2015,43(Database issue):D777-D783
    4. 白冰,章锦曼,苏洁,张杰,靳婵婵,朱宝生,一例Bainbridge-Ropers综合征患儿遗传病因分析,重庆医科大学学报。
    5. Li Yu(#) ,Guo-Dong Wang(#), Jue Ruan(#),Yong-Bin Chen(#),Cui-Ping Yang(#), Xue Cao(#), Hong Wu(#),Yan-Hu Liu(#), Zheng-Lin Du(#), Xiao-Ping Wang(#), Jing Yang, Shao-Chen Cheng ,Li Zhong, Lu Wang ,Xuan Wang, Jing-Yang Hu ,Lu Fang ,Bing Bai ,Kai-Le Wang, Na Yuan ,Shi-Fang Wu ,Bao-Guo Li, Jin-Guo Zhang ,Ye-Qin Yang, Cheng-Lin Zhang ,Yong-Cheng Long ,Hai-Shu Li ,Jing-Yuan Yang, David M Irwin, Oliver A Ryder, Ying Li, Chung-I Wu(*) & Ya-Ping Zhang(*). Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation. Nature Genetics aop,(2016) : doi:10.1038/ng.3615.
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