一、受教育及工作经历 (Education and Work Experience)
1997.09-2001.07, 学士 兰州大学生命科学学院 生物学专业/计算机科学专业(辅修)
2002.07-2009.07, 博士 中国科学院生物物理研究所视觉皮层神经加工机制
2010.4-2016.12, 博士后 杜克大学果蝇神经环路
2016.12-2017.10, 博士后 托马斯杰斐逊大学帕金森疾病的分子机制
2017.10-2021.03, 副研究员 中山大学中山眼科中心灵长类神经生物学及单细胞测序
2021.04-至今, 副教授 昆明理工大学灵长类转化医学研究院 灵长类神经系统的认知功能和疾病研究
Sep. 1997 – Jul. 2001 B.S. major in Biology. Minor in computer. Lanzhou University, Lanzhou, China
Jul. 2002 – Jul. 2009 Ph.D. in neuroscience. Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. Advisor: Bing Li, Ph.D.
Visual information processing in the cat primary visual cortex
Apr. 2010 – Dec. 2016 Duke University Medical Center, Durham, NC Postdoctoral Research Fellow. Advisor: Rebecca Chung-Hui Yang, Ph.D.
Mapping the neural circuits that control behavior in Drosophila melanogaster
Dec. 2016 – 2017.10 Postdoctoral Research Fellow. Department of Neuroscience, Thomas Jefferson. Advisor: Hui Zhang, Ph.D.
Investigating the mechanism of Parkinson disease.
2017.10-2021.03 Associate professor, Zhongshang Ophthalmic Center, Sun Yat-Sen University.
Morphoelectric and Transcriptomic Classification of Primate neurons by using Patch-seq and Single cell sequencing
2021.04-now Associate professor Institute of Primate Translational Medicine, Kunming University of Science and Technology.
二、主要研究方向 (Research Interests)
灵长类高级认知功能的神经机制。
灵长类神经系统疾病的神经机理。
三、科研领域描述 (Description of the Research)
从事神经科学的研究,包括视觉皮层信息加工机制,神经环路的行为机制,神经疾病的机理,灵长类神经系统的单细胞水平的电生理,形态和分子特征。现主要用电生理,光成像,计算建模等手段研究神经系统的认知机制和疾病机理。
四、承担及参与科研项目情况 (Research Projects and Grants)
五、代表性论文和专著(Publications)
1. Se Joon Choi, Jun Mukai, Mirna Kvajo, Bin Xu, Anastasia Diamantopoulou, Pothitos M. Pitychoutis, Bin Gou, Joseph A. Gogos and Hui Zhang. A Schizophrenia-Related Deletion Leads to KCNQ2-Dependent Abnormal Dopaminergic Modulation of Prefrontal Cortical Interneuron Activity. Cerebral Cortex. 2018 Jun 1;28(6):2175-2191.
2. Guntur AR*, Gou B*,Pengyu Gu, Ruo He, Yang Xiang, Stern U and Chung-Hui Yang(2017). H2O2-sensitive isoforms of Drosophila TRPA1 act in bitter-sensing gustatory neurons to promote avoidance of UV during egg-laying. GENETICS, vol. 205 no. 2 749-759.
3. Gou B*, Zhu EY*, He R, Stern U, and Yang CH (2016). High throughput assay to examine egg-laying preferences of individual Drosophila melanogaster. J. Vis. Exp. (109): e53716.
4. Gou B*, Liu Y*, Guntur AR, Stern U, and Yang CH (2014). Mechanosensitive neurons on the internal reproductive tract contribute to egg-laying-induced acetic acid attraction in Drosophila. Cell reports, 9(2): 522-30.
5. Gou B, Li, YH, Li B (2011). Visual response to contrast-defined contours with equally spatial-scaled carrier in cat area 18. Brain Research Bulletin, 86 (1-2): 97-105.
六、课题组成员
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