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Fang Wang, Weiqi Zhang, Qiaoyan Yang , Yu Kang , Yanling Fan, Jingkuan Wei , Zunpeng Liu,Shaoxing Dai , Hao Li, Zifan Li, Lizhu Xu , Chu Chu, Jing Qu, Chenyang Si, Weizhi Ji*,Guang-Hui Liu*, Chengzu Long*, Yuyu Niu*. Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing. Protein Cell (2020). https://doi.org/10.1007/s13238-020-00740-8.29 July 2020
Lifeng Xiang, Yu Yin, Yun Zheng, Yanping Ma, Yonggang Li, Zhigang Zhao, Junqiang Guo, Zongyong Ai, Yuyu Niu, Kui Duan, Jingjing He, Shuchao Ren, Dan Wu, Yun Bai, Zhouchun Shang, Xi Dai, Weizhi Ji, Tianqing Li.A developmental landscape of 3D-cultured human pre-gastrulation embryos.Nature(2019) doi:10.1038/s41586-019-1875-y,12 December 2019
Yuyu Niu*,Nianqin Sun,Chang Li,Ying Lei,Zhihao Huang,Jun Wu,Chenyang Si,Xi Dai,Chuanyu Liu,Longqi Liu,Su Feng,Yu Kang,Wei Si,Hong Wang,E. Zhang,Lu Zhao,Ziwei Li,Xi Luo,Guizhong Cui,Guangdun Peng,Juan Carlos Izpisúa Belmonte*,Weizhi Ji*,Tao Tan*. Dissecting primate early post-implantation development using long-term in vitro embryo culture. Science. 366(6467) :15 Nov 2019
Shanshan Li, Lei Ao, Yaping Yan, Jiang Jiang, Bingbing Chen, Yanchao Duan, Fei Shen, Jinbao Chen,Briauna Inglis, Renmin Ni, Weizhi Ji* and Wei Si*.Differential motility parameters and identification of proteomic profiles of human sperm cryopreserved with cryostraw and cryovial. Clin Proteom. 16, 24 (2019) doi:10.1186/s12014-019-9244-2,19 June 2019
Lei Shi, Xin Luo, Jin Jiang, Yongchang Chen, Cirong Liu, Ting Hu, Min Li, Qiang Lin, Yanjiao Li, Jun Huang, Hong Wang, Yuyu Niu, Yundi Shi, Martin Styner, Jianhong Wang, Yi Lu, Xuejin Sun, Hualin Yu, Weizhi Ji, Bing Su, Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development, National Science Review, Volume 6, Issue 3, May 2019, Pages 480–493,27 March 2019
Hong Wang, Yaping Yan, Xiaoyan Yi, Yanchao Duan, Junfeng Wang, Shanshan Li Lilin Luo, Tianzhuang Huang, Briauna Inglis, Xi Li, Weizhi Ji, Tao Tan* and Wei Si*. Histopathologilal Features and Composition Of Gut Microbiota in Rhesus Monkey of Alcoholic Liver disease Frontiers in Microbiology. Front Microbiol,Volume 10,165. 08 February 2019
Bo Zhang,Zhigang Zhou,Yin Zhou,Ting Zhang,Yuanye Ma,Yuyu Niu,Weizhi Ji,Yongchang Chen.Social-valence-related increased attention in Rett syndrome cynomolgus monkeys: An eye-tracking study. Autism Res. Volume12, Issue11,November 2019,1585-1597,07 August 2019
Tianqing Li*,Zongyong Ai,Weizhi Ji*.Primate stem cells: bridge the translation from basic research to clinic application. SCIENCE CHINA Life Sciences. 2019 62(1):12-21,09 August 2018
Chu Chu, Zhaohui Yang, Jiayin Yang, Li Yan, Chenyang Si, Yu Kang, Zhenzhen Chen, Yongchang Chen,Weizhi Ji and Yuyu Niu*.Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases. BMC Biotechnology. 19, 7 (2019),doi:10.1186/s12896-018-0494-2,15 January 2019
Bin Jiang, Xufeng Fu, Li Yan, Shanshan Li, Dongliang Zhao, Xiaoyan Wang, Yanchao Duan,Yaping Yan, Enqin Li, Kunhua Wu, Briauna Marie Inglis, Weizhi Ji, Ren-He Xu, Wei Si.Transplantation of human ESC-derived mesenchymalstem cell spheroids ameliorates spontaneous osteoarthritis in rhesus macaques. Theranostics. 2019,9(22): 6587–6600. 2019 Aug 21
Li Yan, Bin Jiang, Yuyu Niu, Hongxuan Wang, Enqin Li, Yaping Yan, Huiyan Sun, Yanchao Duan,Shaohui Chang, Guokai Chen, Weizhi Ji*, Ren-He Xu* and Wei Si*.Intrathecal delivery of human ESC-derived mesenchymal stem cell spheres promotes recovery of a primate multiple sclerosis model. Cell Death Discovery. 4, 89 (2018):1551-4005. 20 August 2018
Shuang Wang,Lichuan Yang, Raoxian Bai, Shuaiwei Ren, Yuyu Niu, Weizhi Ji,Yuanye Ma,Yongchang Chen*.Interaction of p53 and ASPPs Regulates Rhesus Monkey Embryonic Stem Cells Conversion to Neural Fate Concomitant with Apoptosis. Cell Cycle. 17(9):1146-1153, 25 Jul 2018
Shuang Wang,Shuaiwei Ren,Raoxian Bai,Puhao Xiao,Qin Zhou,Yin Zhou,Zhigang Zhou,Yuyu Niu,Weizhi Ji and Yongchang Chen.No off-target mutations in functional genome regions of aCRISPR/Cas9-generated monkey model of musculardystrophy. JBC ACCELERATED COMMUNICATION. 293,11654-11658. June 25, 2018
Yiqiang Cui,Yuyu Niu,Jiankui Zhou,Yongchang Chen, Yiwei Cheng, Shangang Li,Zongyong Ai, Chu Chu, Hong Wang, Bo Zheng,Xuejin Chen, Jiahao Sha, Xuejiang Guo,Xingxu Huang, Weizhi Ji. Generation of a precise Oct4-hrGFP knockin cynomolgusmonkey model via CRISPR/Cas9-assisted homologous recombination. Cell Research.28,(2018):383-386. 12 January 2018
Xufeng Fu, Bin Jiang, Bingrong Zheng, Yaping Yan, Junfeng Wang,Yanchao Duan, Shanshan Li, Li Yan, Hong Wang, Bingbing Chen,Xiongbo Sang, Weizhi Ji, Ren-He Xu* and Wei Si*. Heterogenic transplantation of bone marrow-derived rhesus macaque mesenchymal stem cells ameliorates liver fibrosis induced by carbon tetrachloride in mouse. Peer J.6:e4336. February 12, 2018
Yu Kang, Zongyong Ai, Kui Duan, Chenyang Si, Yong Wang, Yun Zheng, Jingjing He, Yu Yin, Shumei Zhao, Baohua Niu, Xiaoqing Zhu, Li Liu, Lifeng Xiang, Linming Zhang, Yuyu Niu, Weizhi Ji, and Tianqing Li*. Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys. Cell Reports. 25(9),2563-2576,27 November 2018
Yuyu Niu, Tianqing Li and Weizhi Ji*.Paving the road for biomedicine: genome editing and stem cells in primates[J]. Stem Cell Research. Volume 4, Issue 4, July 2017, 543–549, 25 August 2017
Fei Gao, Yuyu Niu, Yi Eve Sun, Hanlin Lu, Yongchang Chen, Siguang Li, Yu Kang, Yuping Luo, Chenyang Si, Juehua Yu, Chang Li, Nianqin Sun, Wei Si, Hong Wang, Weizhi Ji*, Tao Tan*.De novo DNA methylation during monkey pre-implantation embryogenesis[J]. Cell Res. 27, 526–539(2017),24 February 2017
Yongchang Chen, Juehua Yu, Yuyu Niu, Dongdong Qin, Hailiang Liu, Gang Li, Yingzhou Hu, Jiaojian Wang, Yi Lu, Yu Kang, Yong Jiang, Kunhua Wu, Siguang Li, Jingkuan Wei, Jing He, Junbang Wang, Xiaojing Liu, Yuping Luo, Chenyang Si, Raoxian Bai, Kunshan Zhang, Jie Liu, Shaoyong Huang, Zhenzhen Chen, Shuang Wang, Xiaoying Chen, Xinhua Bao, Qingping Zhang, Fuxing Li, Rui Geng, Aibin Liang, Dinggang Shen, Tianzi Jiang, Xintian Hu, Yuanye Ma, Weizhi Ji*, Yi Eve Sun*. Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys[J]. Cell. Volume 169, Issue 5, 945-955.e10, 18 May 2017
Bingbing Chen, Shanshan Li, Yaping Yan, Yanchao Duan, Shaohui Chang, Hong Wang, Weizhi Ji*, Xin Wu*, Wei Si*.Cryopreservation of cynomolgus macaque (Macaca fascicularis) sperm with glycerol and ethylene glycol, and its effect on sperm-specific ion channels - CatSper and Hv1. Theriogenology. Volume 104, 37-42,, December 2017
Yan Zhuo, Shuqing Feng, Shaoyong Huang, Xinglong Chen, Yu Kang, Chenyang Si, Zifan Li, Yin Zhou, Ling Zhou, Ting Zhang, Weizhi Ji, Yuyu Niu*, Yongchang Chen*.Transabdominal Ultrasound-guided Multifetal Pregnancy Reduction in 10 Cases of Monkeys. Biology of Reproductio. Volume 97, Issue 5, November 2017, 758–761, 23 October 2017
Xufeng Fu, Yaping Yan, Shanshan Li, Junfeng Wang, Bin Jiang, Hong Wang, Yanchao Duan, Tao Tan, Fei Gao, Desheng Gong, Yuyu Niu, Weizhi Ji*, Bingrong Zheng, Wei Si*.Vitrification of Rhesus Macaque Mesenchymal Stem Cells and the Effects on Global Gene Expression. Stem Cells International. Volume 2017,14 ,24 October 2017
Yongchang Chen, Yuyu Niu, Weizhi Ji. Genome editing in nonhuman primates: approach to generating human disease models[J]. J Intern Med. Volume280, Issue3,September 2016, 246-251. 25 April 2016
Xiaoqing Zhu, Bo Li, Zongyong Ai, Zheng Xiang, Kunshang Zhang, Xiaoyan Qiu, Yongchang Chen, Yuemin Li, Joshua D Rizak, Yuyu Niu, Xintian Hu, Yi Eve Sun, Weizhi Ji*, Tianqing Li*.A Robust Single Primate Neuroepithelial Cell Clonal Expansion System for Neural Tube Development and Disease Studies[J]. Stem Cell Reports. Volume 6, Issue 2,228-242, 9 February 2016
Jingjing He, Zheng Xiang, Xiaoqing Zhu, Zongyong Ai, Jingsong Shen, Tianzhuang Huang, Liegang Liu, Weizhi Ji, Tianqing Li*. Neuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP+-treated Monkeys[J].Scientific Reports.6,34339 (2016),12 October 2016
Zongyong Ai, Zheng Xiang, Yuemin Li, Guoku Liu, Hong Wang, Yun Zheng, Xiaoyan Qiu, Shumei Zhao, Xiaoqing Zhu, Yanhua Li*, Weizhi Ji, Tianqing Li*. Conversion of monkey fibroblasts to transplantable telencephalic neuroepithelial stem cells[J]. Biomaterials. Volume 77, January 2016, Pages 53-65.
Hanlin Lu, Zhimei Yuan, Tao Tan, Junwen Wang, Juyong Zhang, Hui-Juan Luo, Yudong Xia, Weizhi Ji, Fei Gao*. Improved tagmentation-based whole-genome bisulfite sequencing for input DNA from less than 100 mammalian cells[J]. Epigenomics. Vol.7,No.1:47-56.17 Feb 2015
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Haifeng Wan, Chunjing Feng, Fei Teng, Shihua Yang, Baoyang Hu, Yuyu Niu, Andy Peng Xiang, Weizhen Fang, Weizhi Ji, Wei Li, Xiaoyang Zhao, Qi Zhou*. One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system[J]. Cell Res. 25, 258–261 (2015),28 November 2014
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Yu Kang, Bo Zheng, Bin Shen, Yongchang Chen, Lei Wang, Jianying Wang, Yuyu Niu, Yiqiang Cui, Jiankui Zhou, Hong Wang, Xuejiang Guo, Bian Hu, Qi Zhou, Jiahao Sha, Weizhi Ji, Xingxu Huang.* CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH[J]. Hum Mol Genet. Volume 24, Issue 25, 20 December 2015, Pages 7255–7264
Hong Wang, Tao Tan, Junfeng Wang, Yuyu Niu, Yaping Yan, Xiangyu Guo, Yu Kang, Yanchao Duan, Shaohui Chang, Jianpeng Liao, Chenyang Si, Weizhi Ji*, Wei Si. Rhesus monkey model of liver disease reflecting clinical disease progression and hepatic gene expression analysis[J]. Sci Rep. 5, 15019 (2015),07 October 2015
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