张成庭 (Chengting Zhang)

1. 2024.07-至今，昆明理工大学灵长类转化医学研究院，研究员
2. 2023.09-2024.07，昆明理工大学灵长类转化医学研究院，副教授
3. 2018.09-2022.11，英国University of Exeter，博士
4. 2015.09-2018.06，昆明理工大学，硕士
5. 2011.09-2015.06，重庆三峡学院，学士

1. 07/2024-Present Institute of Primate Translational Medicine, Kunming University of Science and Technology, Investigator.
2. 09/2023-07/2024 Institute of Primate TranslationalMedicine, Kunming University of Science and Technology, Associate Professor.
3. 09/2018-11/2022 Living systems institute,University of Exeter, UK, Ph.D.
4. 09/2015-06/2018 Kunming University of Science andTechnology, M.S.
5. 09/2011-06/2015 Chongqing Three Gorges University,B.S.

1. 干细胞与信号转导
2. 解析人早期胚胎发育过程中重要信号传导机制
3. 解析灵长类早期胚胎器官形成过程的具体机制

1. Stem Cells and Signal Transduction
2. Analyzing the important signaling transductionmechanisms during early human embryonic development
3. Analyzing the specific mechanism oforganogenesis in early primate embryos

在多细胞生命体发育过程中，单个细胞之间的有效沟通对于从单个受精卵细胞发育成复杂的成体至关重要。细胞与细胞之间的交流是建立细胞类型多样性、形成组织和器官并最终形成整个生物体的基础。围绕此发育生物学理论，对灵长类早期胚胎发育过程中一系列关键科学问题进行探究。

During the development of all organisms consistingof more than one cell, effective communication between individual cells is vital to allow development from a single fertilised egg cell to a complex adult body. Cell-to-cell communication is fundamental to establishing cell-type diversity, forming tissues and organs, and finally, the entire organism.Based on this developmental biology theory, we aim to explore a series of key scientific questions during early human and primate embryonic development.

1. 国家自然科学基金委员会，青年科学基金项目，FGF信号调控人胚胎围着床期前羊膜腔体形成的机制研究，2025/01-2027/12，主持，30万元。
2. 人力资源社会保障部，高层次留学人才回国资助，2025/01-2027/12，30万元。
3. 国家科技部重点研发专项，人工真核生物线粒体的合成组装及调控，2024/12-2029/12，骨干，250万元。

1. Zhang, C., Brunt,L., Ono, Y. et al. Cytoneme-mediatedtransport of active Wnt5b–Ror2 complexes in zebrafish. (2024). Nature,625 (7993):126-133.
2. Zhang, C., & Scholpp, S. (2019).Cytonemes in development. Current Opinion in Genetics & Development,57, 25-30.
3. Zhang, C., Ma, Y.,Gao, F., Zhao, Y., Cai, S., & Pang, M. (2018). The free, esterified, and insoluble-bound phenolicprofiles of Rhus chinensis Mill. fruits and their pancreatic lipase inhibitory activities with molecular docking analysis. Journal of Functional Foods,40, 729-735.
4. Zhang, C., Ma, Y., Zhao, Y., Hong, Y.,Cai, S., & Pang, M. (2018). Phenolic composition, antioxidant and pancreatic lipase inhibitory activities of Chinese sumac (Rhus chinensis Mill.) fruits extracted by different solvents and interaction between myricetin‐3‐O‐rhamnoside and quercetin‐3‐O‐rhamnoside. International Journal of Food Science &Technology, 53(4), 1045-1053.
5. Rogers, S., Zhang, C.,Anagnostidis, V., Gielen, F., Fishel, M., & Scholpp, S. (2022). Cancer-associated fibroblast-derived ROR2 inducesWNT/PCP activation and polarized migration in receiving gastric cancer cells. PNAS, 120 (39) e2217612120.
6. Rosenbauer, J., Zhang,C., Mattes, B., Reinartz, I., Wedgwood, K., Schindler, S., ... & Schug, A. (2020). Modeling of Wnt-mediatedtissue patterning in vertebrate embryogenesis. PLOS Computational Biology,16(6), e1007417.
7. Huang, S., Ma, Y., Zhang,C., Cai, S., & Pang, M. (2017). Bioaccessibility and antioxidant activity ofphenolics in native and fermented Prinsepia utilis Royle seed during a
   simulated gastrointestinal digestion in vitro. Journal of FunctionalFoods, 37, 354-362.