金丽果（Liguo Jin）

●2025.07-至今: 昆明理工大学灵长类转化医学研究院，副教授，硕士生导师

●2025.07-至今: 省部共建非人灵长类生物医学国家重点实验室，智能响应生物材料平台负责人

●2021.09-2025.06: 天津大学，材料学，工学博士

●2018.09-2021.06: 南昌大学，化学，理学硕士

●2014.09-2018.06: 曲靖师范学院，化学，理学学士

●2025.07-Present: Institute of Primate Translational Medicine, Kunming University of Science and Technology, Associate Professor, Supervisor

●2025.07-Present: Provincial and Ministry Joint State Key Laboratory of Non-human Primates Biomedical Research‌, Principal Investigator in Intelligent Responsive Biomaterials Platform

●2021.09-2025.06: Tianjin University, Materials Science, Doctor of Philosophy (Ph.D.)

●2018.09-2021.06: Nanchang University, Chemistry, Master of Science (M.S.)

●2014.09-2018.06: Qujing Normal University, Chemistry, Bachelor of Science (B.S.)

1. 研究智能生物材料在微波/超声/近红外光等多模态物理信号调控下，通过协同抗菌、抗炎与成骨作用机制，实现对组织免疫微环境的精准调控与骨再生修复。

2. 研究智能生物材料介导的微波/超声/近红外光能量耦合与传递机制及其对血脑屏障的时空精准调控研究。

3. 研究灵长类神经系统疾病的新型非侵入性神经调控与靶向给药技术，重点优化微波/超声/近红外光的能量参数与智能生物材料设计。

4. 开发基于智能生物材料平台与微波/超声/近红外光等多模态物理能量耦合的远程调控系统，实现对移植神经干细胞增殖、分化和功能成熟的精准调控。

5. 基于智能生物材料构建能量响应型微针系统，探索利用微波/超声/近红外光远程精准调控药物递送与释放行为，突破血脑屏障治疗神经系统疾病的新机制。

1. Research on intelligent biomaterials under the control of multimodal physical signals such as microwave, ultrasound, and near-infrared light, through synergistic antibacterial, anti-inflammatory, and osteogenic mechanisms, to achieve precise control of the tissue immune microenvironment and bone regeneration and repair.

2. Research on the mechanism of microwave/ultrasound/near-infrared light energy coupling and transmission mediated by smart biomaterials and its spatiotemporal precise regulation of the blood-brain barrier.

3. Research into novel non-invasive neuromodulation and targeted drug delivery technologies for primate neurological disorders, with a focus on optimizing the energy parameters of microwave/ultrasound/near-infrared light and the design of smart biomaterials.

4. Develop a remote control system based on an intelligent biomaterial platform and multimodal physical energy coupling such as microwave/ultrasound/near-infrared light to achieve precise control of the proliferation, differentiation, and functional maturation of transplanted neural stem cells.

5. Based on intelligent biomaterials, an energy-responsive microneedle system has been developed to explore the use of microwave/ultrasound/near-infrared light for remote, precise control of drug delivery and release behavior, thereby breaking through the blood-brain barrier to treat neurological diseases through a new mechanism.

团队聚焦于智能响应型生物材料与多模态物理能量（微波/超声/近红外光）的交叉融合，致力于发展一类具有能量耦合与时空调控功能的生物医学平台，旨在解决组织再生与神经系统疾病治疗中的关键难题。在骨再生方向，研究重点在于通过材料在物理信号调控下协同调控抗菌、抗炎及成骨微环境，实现免疫微环境重塑与高质量骨修复。在神经科学方向，系统探索物理能量和材料介导的血脑屏障可逆、精准开放机制，建立远程非侵入性的药物递送与神经免疫调控新策略，显著提升灵长类神经系统疾病的干预效果。

The team focuses on the cross-integration of intelligent responsive biomaterials and multimodal physical energy (microwave/ultrasound/near-infrared light), dedicated to developing a biomedical platform with energy coupling and time-controlled functions, aiming to solve key challenges in tissue regeneration and the treatment of neurological diseases. In the field of bone regeneration, research focuses on the synergistic regulation of antibacterial, anti-inflammatory, and osteogenic microenvironments through materials under physical signal control, thereby achieving immune microenvironment remodeling and high-quality bone repair. In the field of neuroscience, we are systematically exploring the reversible and precise opening mechanisms of the blood-brain barrier mediated by physical energy and materials. We aim to establish new strategies for remote, non-invasive drug delivery and neuroimmunomodulation, significantly enhancing the efficacy of interventions for neurological disorders in primates.

1. 2024年中国科协青年人才托举工程博士生专项

2. 2023年博士研究生国家奖学金

3. 2020年硕士研究生国家奖学金

4. 2017年本科生国家奖学金

5. 2016年本科生国家励志奖学金

6. 2017年中国电信奖学金飞Young奖

7. 2018年中国大学生自强之星奖学金

8. 2024年宝钢优秀学生奖学金

9. 2022年苏州育才奖学金

10. 2024年第六届优秀科技作品竞赛全国三等奖

11. 2016年高等院校教学素质大赛全国二等奖

12. 2023年第五届抗菌科学与技术论坛优秀墙报三等奖

13. 2017年我与外教全国征文比赛“枫叶杯”全国优秀奖

14. 2016年第六届高校文化节网络原创小说大赛云南省三等奖

15. 2017年第三届互联网+大学生创新创业比赛云南省铜奖

16. 2015年全国大学生英语竞赛云南省优秀奖

17. 2016-2018连续三年云南省三好学生荣誉称号

18. 2024年天津大学优秀学生标兵奖学金

19. 2025年天津大学十佳杰出青年荣誉称号

20. 2024年天津大学博士生学术论坛优秀口头报告奖

1. 王小磊; 金丽果. 一种抑郁症快速治疗的复合物及其制备方法和应用, 2023-03-14, 中国, ZL201911187887.9

1. Liguo Jin, Ping Hu, Yinyin Wang, Luojia Wu, Kang Qin, Haoxin Cheng, Shuhua Wang, Bingxing Pan, Hongbo Xin, Wenhua Zhang*, Xiaolei Wang*. Fast-Acting Black-Phosphorus-Assisted Depression Therapy with Low Toxicity. Advanced Materials, 2020, 32(2), 1906050. (中科院 TOP 一区，IF: 30.8)

2. Liguo Jin, Hanpeng Liu, Chaofeng Wang, Congyang Mao, Shuilin Wu*, Yu Zhang, Zhaoyang Li, Shengli Zhu, Hui Jiang, Zhenduo Cui, Yufeng Zheng, Xiangmei Liu*. Interface/Dipole Polarized Antibiotics-Loaded Fe3O4/PB Nanoparticles for Non-Invasive Therapy of Osteomyelitis under Medical Microwave Irradiation. Advanced Materials, 2024, 36(47), 2410917. (中科院 TOP 一区，IF: 26.8)

3. Liguo Jin, Shuilin Wu*, Congyang Mao, Chaofeng Wang, Shengli Zhu, Yufeng Zheng, Yu Zhang, Zhaoyang Li, Zhenduo Cui, Hui Jiang, Xiangmei Liu*. Rapid and Effective Treatment of Chronic Osteomyelitis by Conductive Network-Like MoS2/CNTs through Multiple Reflection and Scattering Enhanced Synergistic Therapy. Bioactive Materials, 2024, 31, 284-297. (中科院 TOP 一区，IF: 20.3)

4. Liguo Jin, Xiangmei Liu, Yufeng Zheng, Zhaoyang Li, Yu Zhang, Shengli Zhu, Hui Jiang, Zhenduo Cui, Paul K. Chu, Shuilin Wu*. Interface Polarization Strengthened Microwave Catalysis of MoS2/FeS/Rhein for the Therapy of Bacteria-Infected Osteomyelitis. Advanced Functional Materials, 2022, 32(33), 2204437. (中科院 TOP 一区，IF: 19.0)

5. Liguo Jin, Xiangmei Liu, Yufeng Zheng, Yu Zhang, Zhaoyang Li, Shengli Zhu, Hui Jiang, Zhenduo Cui, Shuilin Wu*. Interfacial and Defect Polarization Enhanced Microwave Noninvasive Therapy for Staphylococcus aureus-Infected Chronic Osteomyelitis. ACS Nano, 2023, 17(18), 18200-18216. (中科院 TOP 一区，IF: 15.8)

6. Liguo Jin, Hanpeng Liu, Congyang Mao, Chaofeng Wang, Shuilin Wu*, Khin Wee Lai*, Yu Zhang, Zhaoyang Li, Shengli Zhu, Hui Jiang, Zhenduo Cui, Jie Shen, Yufeng Zheng, Xiangmei Liu*. Multivariant Interfacial/Ferroelectric/Dipole Polarization Strengthened Microwave-Catalysis Eradicates Deep Bacteria-Infected Osteomyelitis. Journal of Materials Science & Technology, 2025, 232, 313-324. (中科院 TOP 一区，IF: 14.3)

7. Liguo Jin, Yufeng Zheng, Xiangmei Liu, Yu Zhang, Zhaoyang Li, Yanqin Liang, Shengli Zhu, Hui Jiang, Zhenduo Cui, Shuilin Wu*. Magnetic Composite Rapidly Treats Staphylococcus aureus-Infected Osteomyelitis through Microwave Strengthened Thermal Effects and Reactive Oxygen Species. Small, 2022, 18(41), 2204028. (中科院 TOP 一区，IF: 13.3)

8. Liguo Jin, Hanpeng Liu, Chaofeng Wang, Xiangmei Liu*, Congyang Mao, Yu Zhang*, Zhaoyang Li, Shengli Zhu, Hui Jiang, Zhenduo Cui, Yufeng Zheng, Shuilin Wu*. A Bacterial Capturing, Neural Network-Like Carbon Nanotubes/Prussian Blue/Puerarin Nanocomposite for Microwave Treatment of Staphylococcus aureus-Infected Osteomyelitis. Small, 2024, 20(52), 2407113. (中科院二区，IF: 12.1)

9. Liguo Jin, Haoxin Cheng, Xuanping Xie, Xinyu Chen, Guangqi Tian, Zhenling Zhu, Shuhua Wang, Hongbo Xin, Xiaolei Wang*. Dual-Effective Chronic Wounds Management System through a Monoglyceride Binary Blend Matrix Based Thermal-Responsive Phase-Transition Substrate. Advanced Healthcare Materials, 2021, 10(8), 2001966. (中科院二区，IF: 11.1)

10. Liguo Jin, Yinyin Wang, Huan Ouyang, Yu Liu, Zhenling Zhu, Shuhua Wang, Hongbo Xin, Xiaolei Wang*. A Versatile and Low-Toxicity Material for Photothermal Therapy in Deeper Tissues. Journal of Materials Chemistry B, 2021, 9(31), 6155-6162. (中科院二区，IF: 7.6)

11. Hanpeng Liu, Liguo Jin, Shengli Zhu, Congyang Mao, Shuilin Wu*, Chaofeng Wang,Yufeng Zheng, Zhaoyang Li, Hui Jiang, Zhenduo Cui, Xiangmei Liu*. Motion-Activating Pliable Carbon Nanofiber for Smart Mechanosensitive Sensing and Antibacterial Protection. Advanced Functional Materials, 2025, 35(7), 2415258. (中科院 TOP 一区，IF: 19.0)

12. Mingxue Shi, Liguo Jin, Chaofeng Wang, Congyang Mao, Xiangmei Liu*, Zhaoyang Li*, Shengli Zhu, Hui Jiang, Zhenduo Cui, Yufeng Zheng, Shuilin Wu*. Diverse Loss Mechanism Enhanced Microwave Thermal Effects of Capacitor-Like Structure Ti3C2Tx MXene/CNT for Rapid Treatment of Osteomyelitis. Chemical Engineering Journal, 2025, 507, 160540. (中科院 TOP 一区，IF: 13.2)

13. Wenjing Zhang, Liguo Jin, Shuilin Wu*, Chaofeng Wang, Yufeng Zheng, Zhaoyang Li, Zhenduo Cui, Hui Jiang, Shengli Zhu, Xiangmei Liu*. Microwave Excited Hyperthermy and Catalysis of Heterostructured Au/Cu-BTA for Effective Bacteria killing by Accelerating Charge Separation. Rare Metals, 2024, 43(10), 5186-5201. (中科院 TOP 一区，IF: 11.0)

14. Hanpeng Liu, Liguo Jin, Shengli Zhu, Shuilin Wu*, Congyang Mao, Chaofeng Wang, Yufeng Zheng, Zhaoyang Li, Hui Jiang, Zhenduo Cui, Paul K. Chu, Xiangmei Liu*. Interfacial Electronic Modulation on Polyaniline/Curcumin Fiber for Photo-Powered Rapid Wound Healing. Nano Today, 2024, 57, 102397. (中科院二区，IF: 10.9)

15. Yue Wang, Liguo Jin, Chaofeng Wang, Hanpeng Liu, Congyang Mao, Xiangmei Liu*, Zhaoyang Li*, Shengli Zhu, Hui Jiang, Zhenduo Cui, Yufeng Zheng, Shuilin Wu*. Microwave-Excited Thermoelectric Catalysis of Organic-Inorganic Nanohybrid for Highly Effective Treatment of S. aureus-Infected Osteomyelitis. Small, 2025, 21(18): 2500915. (中科院二区，IF: 12.1)

16. Zhenling Zhu, Liguo Jin, Fen Yu, Feifei Wang, Zhenzhen Weng, Jia Liu, Zhen Han, Xiaolei Wang*. ZnO/CPAN Modified Contact Lens with Antibacterial and Harmful Light Reduction Capabilities. Advanced Healthcare Materials, 2021, 10(13), 2100259. (中科院二区，IF: 11.1)

17. Cuihong Chen, Zhenxing Yang, Congyang Mao, Liguo Jin, Shuilin Wu, Yufeng Zheng, Zhenduo Cui, Zhaoyang Li, Yu Zhang, Shengli Zhu, Hui Jiang, Xiangmei Liu*. A Smart Nanovector of Cationic Starch Modified Curcumin with Excellent Targeting and Sonodynamic Properties for Effective Therapy of MRSA-Induced Osteomyelitis. Advanced Functional Materials, 2023, 33(52), 2308437. (中科院 TOP 一区，IF: 18.5)

18. Yuelin Lv, Cuihong Chen, Liguo Jin, Yufeng Zheng, Shuilin Wu*, Yu Zhang, Zhaoyang Li, Shengli Zhu, Hui Jiang, Zhenduo Cui, Xiangmei Liu*. Microwave-Excited, Antibacterial Core-Shell BaSO4/BaTi5O11@PPy Heterostructures for Rapid Treatment of S. aureus-Infected Osteomyelitis. Acta Biomaterialia, 2023, 167, 506-518. (中科院 TOP 一区，IF: 9.4)

19. Cuihong Chen, Lin Chen, Congyang Mao, Liguo Jin, Shuilin Wu, Yufeng Zheng, Zhenduo Cui, Zhaoyang Li, Yu Zhang, Shengli Zhu, Hui Jiang, Xiangmei Liu*. Natural Extracts for Antibacterial Applications. Small, 2024, 20(9), 2306553. (中科院二区，IF: 12.1)

20. Jinzhi Ren, Yuqian Qiao, Liguo Jin, Congyang Mao, Chaofeng Wang, Shuilin Wu*, Yufeng Zheng, Zhaoyang Li, Zhenduo Cui, Hui Jiang, Shengli Zhu, and Xiangmei Liu*. A Smart Bacteria-Capture-Killing Vector for Effectively Treating Osteomyelitis through Synergy under Microwave Therapy. Small, 2024, 20(15), 2307406. (中科院二区，IF: 12.1)

21. Qiyao Zheng, Xiangmei Liu*, Congyang Mao, Hanpeng Liu, Liguo Jin, Chaofeng Wang, Shengli Zhu, Yufeng Zheng, Zhaoyang Li, Hui Jiang, Zhenduo Cui, Yu Zhang, Paul K Chu, Shuilin Wu*. Tribovoltaic Effect Strengthened Microwave Catalytic Antibacterial Composite Hydrogel. Advanced Healthcare Materials, 2024, 13(31), 2402266. (中科院二区，IF: 9.6)

22. Hongbo Wang, Chaofeng Wang, Shuilin Wu, Danning Yan, Caihui Huang, Congyang Mao, Yufeng Zheng, Hanpeng Liu, Liguo Jin, Shengli Zhu, Zhaoyang Li, Hui Jiang, Xiangmei Liu*. Accelerating Interface NIR-Induced Charge Transfer Through Cu and Black Phosphorus Modifying G-C3N4 for Rapid Healing of Staphylococcus aureus Infected Diabetic Ulcer Wounds. Small, 2025, 21(20), 2500378. (中科院二区，IF: 12.1)

23. Yingde Xu, Honggang Xia, Chaofeng Wang, Xiangmei Liu*, Hangpeng Liu, Liguo Jin, Hui Jiang, Zhenduo Cui, Yanqin Liang, Shuilin Wu*, Shengli Zhu, Zhaoyang Li*. Calcination-Induced Tight Nano-Heterointerface for Highly Effective Eradication of Rib Fracture-Related Infection by Near-Infrared Irradiation. ACS Applied Materials & Interfaces, 2025, 17, 9854-9866. (中科院二区，IF: 8.2)

24. Manyu Wang, Xinyan Cheng, Lin Luo, Yu Liu, Fei Cao, Siyu Zhao, Haichuan Peng, Can Hong, Liguo Jin, Libin Deng, Hongbo Xin, Xiaolei Wang*. A Multi-Effective and Long-Acting Immunotherapy through One Single Hydrogel Based Injection. Biomaterials Science, 2021, 9, 1374-1380. (中科院二区，IF: 7.6)