吴成新 (Chengxin Wu)

1. 2023.11-至今，昆明理工大学灵长类转化医学研究院，副教授

2. 2019.09-2023.07，东北大学，博士

3. 2016.09-2019.06，兰州大学，硕士
4. 2012.09-2016.06，兰州大学，学士

 
1. 11/2023-Present, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Associate Professor
2. 09/2019-07/2023, Northeastern University, Ph.D.
3. 09/2016-06/2019, Lanzhou University, M.S.
4. 09/2012-06/2016, Lanzhou University, B.S.

1. 超高分辨三维组织成像技术研究

2. 多光子活体显微成像技术研究

3. 在体流式分析系统创制与应用研究

1. Research onUltra-high-resolution 3D Tissue Imaging Technology

2. Research on inVivo Multi-photon Imaging Technique

3. Developmentand Application of in Vivo Flow Cytometry 

基于组织透明化等样品前处理技术，以及超高分辨显微系统和激光片层扫描显微系统，开展脑、早期胚胎、类器官等的高分辨三维成像技术研究。同时，基于活体成像视窗植入以及在体荧光标记技术，结合双光子共聚焦显微系统，探索脑、脊柱等的在体多光子显微成像方法。充分利用先进影像平台的技术及设备资源，为灵长类生殖与发育调控机制研究、灵长类干细胞与组织工程，以及灵长类动物模型与疾病机制研究提供先进的生物影像技术支持。

Utilizing sample pre-processing techniques such as tissue clearing, along with ultra-high-resolution microscopy systems and laser sheet scanning microscopy, we aim to conduct high-resolution 3D imaging research on the brain, early embryos, and organoids. Meanwhile, by integrating in vivo imaging window implantation, in vivo fluorescent labeling, and two-photon confocal microscopy imaging, we aim to explore in vivo multi-photon microscopic imaging methods for the brain, spinal cord, and others. We are committed to leveraging the technology and equipment of advanced imaging platform to provide cutting-edge biological imaging support for studies on primate reproductive and developmental regulation mechanisms, primate stem cell and tissue engineering, as well as primate animal models and disease mechanisms.

1. ChengxinWu; Xue Men;Meijun Liu; Yujia Wei; Xing Wei; Yong-Liang Yu; Zhang-Run Xu; MingLi Chen; Jian-Hua Wang ; Two-Dimensional Multi-parameter Cytometry Platform for Single-Cell Analysis, Analytical Chemistry, 2023, 95(35):13297-13304.
2. ChengxinWu; XingWei; Xue Men; Xuan Zhang; Yong-Liang Yu; Zhang-Run Xu; Ming-Li Chen; Jian-Hua Wang ; Two-Dimensional Cytometry Platform for Single-Particle/Cell Analysis with Laser-Induced Fluorescence and ICP–MS, Analytical Chemistry,2021, 93(23): 8203-8209.
3. ChengxinWu; XingWei; Xue Men; Yulong Xu; Junjie Bai; Yu Wang; Lei Zhou; Yong-Liang Yu; Zhang-Run Xu; Ming-Li Chen; Jian-Hua Wang ; Open flow cytometer with the combination of 3D hydrodynamic single cell focusing and confocal laser-induced fluorescence detection, Talanta, 2023, 258: 124424.
4. ChengxinWu; YuanyuanSun; Yuanhang Wang; Wenzhen Duan; Jiangyue Hu; Lei Zhou; Qiaosheng Pu ; 7-(Diethylamino)coumarin-3-carboxylic acid as derivatization reagent for 405 nm laser-induced fluorescence detection: A case study for the analysis of sulfonamides by capillary electrophoresis, Talanta, 2019, 201:16-22.
5. ChengxinWu; WeiWang; Feifei Quan; Pengfei Chen; Jiali Qian; Lei Zhou; Qiaosheng Pu ; Sensitive analysis of curcuminoids via micellar electrokinetic chromatography with laser-induced native fluorescence detection and mixed micelles-induced fluorescence synergism, Journal of Chromatography A, 2018,1564(1564): 207-213.