王骄健（Jiaojian Wang）

王骄健，昆明理工大学灵长类转化医学研究院，教授，博士生导师。云南省杰青、云南省兴滇英才青年人才。博士毕业于电子科技大学生物医学工程专业，在美国宾夕法尼亚大学从事博士后研究。长期致力于跨物种、跨尺度神经精神疾病机制及精准治疗研究。主持国家青年科学基金、面上项目、科技创新2030-“脑科学与类脑研究”重大项目子课题、云南省杰出青年项目、云南省科技厅联合重点、四川省科技厅等项目。近5年以最后通讯作者在领域内权威期刊Nature Communications, Advanced Science, eLife，npj Parkinson’s Disease, Cerebral Cortex，Human Brain Mapping, Translational Psychiatry等发表SCI论文40余篇，ESI 1%高被引论文7篇。文章被引用9000余次，授权国家发明专利2项。获得山东省科技进步二等奖、中国人工智能学会2020年度优秀科技成果奖、昆明理工大学灵长类转化医学研究院2025年杰出研究奖和生物医学创新基金青年研究奖。入选Research.com2024中国最佳神经科学家。

课题组于2022年3月正式组建，灵长类磁共振研究中心主要研究方向包括：利用磁共振成像研究灵长类发育、衰老图谱；灵长类神经精神疾病神经生物学机制；神经精神疾病治疗及临床转化应用。此外，团队负责研究院磁共振平台的建设、运维及相关研究，参与和支持研究院内各课题组的磁共振影像分析。

1. 国家自然科学基金面上项目“基于抑郁环路精细脑图谱研究抑郁症电休克治疗神经机制和个体化预测”，2022-2025，59万元

2. 科技创新2030-“脑科学与类脑研究”重大项目：基于脑疾病模型猴的治疗，2021-2026，339.3万元

3. 云南省基础研究专项-杰出青年项目：脑连接图谱，2025-2028，50万元

2009.09 – 2014.12 电子科技大学，生物医学工程，博士（硕博连读）

2005.09 – 2009.06 四川农业大学，农业电气化与自动化，学士

2022.03 – 至今 昆明理工大学，灵长类转化医学研究院，教授

2019.08 – 2022.02 电子科技大学，生命科学与技术学院，副教授

2015.03 – 2019.07 电子科技大学，生命科学与技术学院，讲师

2017.07 – 2018.08 宾夕法尼亚大学，Perelman医学院，博士后

云南神经科学学会监事长

中国图象图形学学会脑图谱专委会委员

中国医学装备协会脑网络神经外科分会委员

Frontiers in Neuroscience、Frontiers in Human Neuroscience杂志副主编；Scientific Reports编委；Psychoradiology杂志青年编委

近5年代表性成果：
1. Jin Chen, Yuning Zhang, Shu Liu, Miguel Garcia-Argibay, Tianye Jia, Jujiao Kang, Wei Li, Marco Solmi, Hongyi Sun, Wenqi Liu, Congying Chu*, Samuele Cortese*, Jiaojian Wang* (通讯作者), (2025). Neural-genetic-environmental evidence for a disease factor in mental and physical health multimorbidity. Nature Communications , 16(1), 10088.

2. Wei Li, Xia Qiu, Jin Chen, Kexuan Chen, Meiling Chen, Yinyan Wang, Wenjie Sun, Jing Su, Yongchang Chen, Xiaobao Liu*, Congying Chu*, Jiaojian Wang* (通讯作者), (2025). Disentangling the Switching Behavior in Functional Connectivity Dynamics in Autism Spectrum Disorder: Insights from Developmental Cohort Analysis and Molecular-Cellular Associations. Advanced Science , 12(20):e2403801.

3. Yue Li, Qinyao Sun, Shunli Zhu, Congying Chu*, Jiaojian Wang* (通讯作者), (2024). Cross-species alignment along the chronological axis reveals evolutionary effect on structural development of the human brain. eLife , 13: e96020.

4. Futing Yang, Junyi Shen, Lingli Tan, Rucheng Yang, Lina Zhu, Heng Shao, Jianhong Hou， Zanzong Sun*, Yuan Gao*, Yanbing Hou*, Jiaojian Wang* (通讯作者), (2025). Mapping the Neural and Molecular Basis Underlying Fatigue in Parkinson’s disease. NPJ Parkinson's disease, 12(1), 3.

5. Qinyao Sun, Shunli Zhu, Futing Yang, Zhigang Chen, Heling Li, Heng Shao*, Hong Wang*, Sangma Xie*, Jiaojian Wang* (通讯作者), (2025). Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques. Neuroscience Bulletin , doi: 10.1007/s12264-025-01460-x.

6. Hui Sun, Hongjie Cui, Qinyao Sun, Yuanyuan Li, Tongjian Bai, Kai Wang, Jiang Zhang*, Yanghua Tian*, Jiaojian Wang* (通讯作者), (2024). Individual large-scale functional network mapping for major depressive disorder with electroconvulsive therapy, Journal of Affective Disorders, 360:116-125. doi: 10.1016/j.jad.2024.05.141.

7. Kexuan Chen, Yingzi Ma, Rui Yang, Fang Li, Wei Li, Jin Chen, Heng Shao, Chongjun He, Meiling Chen*, Yuejia Luo*, Bochao Cheng*, Jiaojian Wang* (通讯作者), (2024). Shared and disorder-specific large-scale intrinsic and effective functional network connectivities in postpartum depression with and without anxiety. Cerebral Cortex, 34(12):bhae478.

8. Kexuan Chen, Jia Yang, Fang Li, Jin Chen, Meiling Chen, Heng Shao, Chongjun He, Defang Cai, Xing Zhang, Libo Wang, Yuejia Luo*, Bochao Cheng*, Jiaojian Wang* (通讯作者), (2024). Molecular basis underlying default mode network functional abnormalities in postpartum depression with and without anxiety, Human Brain Mapping, 45(5), e26657. doi: 10.1002/hbm.26657. (ESI 1%高被引论文)

9. Xiaohui Yu, Kexuan Chen, Yingzi Ma, Tongjian Bai, Shunli Zhu, Defang Cai, Xing Zhang, Kai Wang, Yanghua Tian*, Jiaojian Wang* (通讯作者), (2024). Molecular basis underlying changes of brain entropy and functional connectivity in major depressive disorders after electroconvulsive therapy, CNS Neuroscience & Therapeutics, 30(3), e14690. doi: https://doi.org/10.1111/cns.14690. (ESI 1%高被引论文)

10. Hui Sun, Qinyao Sun, Yuanyuan Li, Jiang Zhang*, Haoyang Xing*, Jiaojian Wang* (通讯作者), (2024). Mapping individual structural covariance network in development brain with dynamic time warping. Cerebral Cortex, 34(2), bhae039. doi: 10.1093/cercor/bhae039.

11. Jiang Zhang, Zhiwei Zhang, Hui Sun, Yingzi Ma, Jia Yang, Kexuan Chen, Xiaohui Yu, Tianwei Qin, Tianyu Zhao, Jingyue Zhang, Congying Chu & Jiaojian Wang* (通讯作者), (2024). Personalized functional network mapping for autism spectrum disorder and attention-deficit/hyperactivity disorder, Translational Psychiatry, 14(1), 92. doi: 10.1038/s41398-024-02797-z.

12. Jia Yang, Kexuan Chen, Junyu Zhang, Yingzi Ma, Meiling Chen, Heng Shao, Xing Zhang, Defang Fan, Zhengbo Wang*, Zhenglong Sun*, Jiaojian Wang* (通讯作者), (2023). Molecular mechanisms underlying human spatial cognitive ability revealed with neurotransmitter and transcriptomic mapping. Cerebral Cortex, 33(23), 11320-11328.

13. Bochao Cheng, Yi Guo , Xijian Chen, Bin Lv, Yi Liao, Haibo Qu, Xiao Hu, Haoxiang Yang, Yajing Meng, Wei Deng, Jiaojian Wang* (通讯作者), (2022). Postpartum depression and major depressive disorder: the same or not? Evidence from resting-state functional MRI, Psychoradiology, 2, 121–128.

14. Yuanyuan Li, Xiaohui Yu, Yingzi Ma, Jing Su, Yue Li, Shunli Zhu, Tongjian Bai, Qiang Wei, Benjamin Becker, Zhiyong Ding, Kai Wang, Yanghua Tian*, Jiaojian Wang* (通讯作者), (2023). Neural signatures of default mode network in major depression disorder after electroconvulsive therapy, Cerebral Cortex, 33(7):3840-3852.

15. Jiang Zhang, Tianyu Zhao, Jingyue Zhang, Zhiwei Zhang, Hongming Li, Bochao Cheng, Yajing Pang*, Huawang Wu*, Jiaojian Wang* (通讯作者), (2022). Prediction of childhood maltreatment and subtypes with personalized functional connectome of large-scale brain networks, Human Brain Mapping, 43(15), 4710– 4721.

16. Jingjing Gao, Mingren Chen, Die Xiao, Yue Li, Shunli Zhu, Yanling Li, Xin Dai, Fengmei Lu, Zhengning Wang, Shimin Cai*, Jiaojian Wang* (通讯作者), (2023). Classification of major depressive disorder using an attention-guided unified deep convolutional neural network and individual structural covariance network, Cerebral Cortex, 33(6):2415-2425.

17. Bochao Cheng, Xiuli Wang, Neil Roberts, Yushan Zhou, Song Wang, Pengcheng Deng, Yajing Meng, Wei Deng, Jiaojian Wang* (通讯作者), (2022). Abnormal dynamics of resting-state functional activity and couplings in postpartum depression with and without anxiety, Cerebral Cortex, 32(24):5597-5608. (ESI 1%高被引论文)

18. Yajing Pang, Shanshan Zhao, Zhihui Li, Nan Li, Jiarui Yu, Rui Zhang, Fengmei Lu, Heng Chen, Fengchun Wu, Wei Zheng, Jingjing Gao, Yongfeng Yang*, Huawang Wu*, Jiaojian Wang* (通讯作者), (2022). Enduring effect of abuse: Childhood maltreatment links to altered theory of mind network among adults. Human Brain Mapping, 43(7):2276-2288. (ESI 1%高被引论文)

19. Bochao Cheng, Neil Roberts, Yushan Zhou, Xiuli Wang, Yuanyuan Li, Yiming Chen, Yajun Zhao, Pengcheng Deng, Yajing Meng, Wei Deng & Jiaojian Wang* (通讯作者), (2022). Social support mediates the influence of cerebellum functional connectivity strength on postpartum depression and postpartum depression with anxiety. Translational Psychiatry, 12(1):54. (ESI 1%高被引论文)

20. Yajing Pang, Qiang Wei, Shanshan Zhao, Nan Li, Zhihui Li, Fengmei Lu, Jianyue, Pang, Rui Zhang, Kai Wang, Congying Chu*, Yanghua Tian*, Jiaojian Wang* (通讯作者). (2022). Enhanced default mode network functional connectivity links with electroconvulsive therapy response in major depressive disorder. Journal of Affective Disorders, 306, 47-54. (ESI 1%高被引论文)

21. Bochao Cheng, Yushan Zhou, Veronica P Y Kwok, Yuanyuan Li, Song Wang, Yajun Zhao, Yajing Meng, Wei Deng, Jiaojian Wang* (通讯作者), (2022). Altered functional connectivity density and couplings in postpartum depression with and without anxiety. Social Cognitive and Affective Neuroscience, 17(8):756-766.

22. Jiaojian Wang, Zhengbo Wang, Hongjiang Zhang, Shufei Feng, Yi Lu, Shuang Wang, Hong Wang, Yi Eve Sun, Yongchang Chen*, (2021). White Matter Structural and Network Topological Changes Underlying the Behavioral Phenotype of MECP2 Mutant Monkeys. Cerebral Cortex, 31(12):5396-5410.

23. Jiang Zhang, Dundi Xu, Hongjie Cui, Tianyu Zhao, Congying Chu, Jiaojian Wang* (通讯作者), (2021). Group-guided individual functional parcellation of the hippocampus and application to normal aging. Human Brain Mapping, 42(18), 5973– 5984.

24. Jiaojian Wang, Yang Yang, Xudong Zhao, Zhentao Zuo*, Li-Hai Tan*. (2020). Evolutional and developmental anatomical architecture of the left inferior frontal gyrus. NeuroImage 222, 117268.

25. Zhao Gao, Xin Guo, Cirong Liu, Yin Mo*, Jiaojian Wang* (通讯作者). (2020). Right inferior frontal gyrus: An integrative hub in tonal bilinguals. Human Brain Mapping 41(8):2152-2159.

26. Jinping Xu, Qiang Wei, Tongjian Bai, Lijie Wang, Xuemei Li, Zhengyu He, Jianhuang Wu, Qingmao Hu, Xun Yang, Chao Wang, Yanghua Tian*, Jiaojian Wang* (通讯作者) & Kai Wang. (2020). Electroconvulsive therapy modulates functional interactions between submodules of the emotion regulation network in major depressive disorder. Translational Psychiatry 10, 271.

灵长类磁共振研究中心目前有教授1人，副教授1人，科研助理1人共计3人，4名在读博士研究生，7名在读硕士研究生，以及4名客座访问学生。

欢迎有脑科学、磁共振成像、以及认知神经科学、神经生物学感兴趣的学生加入；对具有图像/信号处理经验优先；熟悉Matlab，Python等计算机编程语言，拥有计算机、生物医学工程等工科背景优先考虑。