杨泽斌（Zebin Yang）

• 2022.09-至今 昆明理工大学灵长类转化医学研究院，副教授，硕士生导师
• 2019.01-2022.06 中国科学院上海硅酸盐研究所，联合培养博士
• 2018.09-2022.06 同济大学，化学，理学博士
• 2015.09-2018.06 昆明理工大学，材料学，工学硕士
• ep 2022-present Institute of Primate Translational Medicine, Kunming University of Science and Technology, Associate Professor.
• Jan 2019-June 2022 joint Ph.D., Shanghai Institute of Ceramics, Chinese Academy of Sciences.
• Sep 2018-June 2022 Ph.D., Chemistry, Tongji University.
• Sep 2015-June 2018 M.S., Materials Science, Kunming University of Science and Technology.

1.智能响应型纳米递送系统的构建

2.肿瘤免疫微环境的重塑研究

3.基于CRISPR/Cas9编辑技术在疾病中的靶向治疗

1.Construction of intelligent responsive nano-delivery system

2.Focus on the remodeling of tumor immune microenvironment

3.Targeted therapy in diseases based on CRISPR/Cas9 editing technology

肿瘤免疫抑制微环境是诱导肿瘤复发转移的根本原因。综合纳米技术、材料学和生物医学，以药物或基因技术（CRISPR/Cas9）作为手段，通过构建智能响应型纳米递送系统，实现对肿瘤免疫微环境的有效调控，降低癌症的复发转移。为临床的精准、安全、有效的癌症治疗提供一种新的思路。

The tumor immunosuppressive microenvironment is the primary cause of cancer metastasis and recurrence. Integrating nanotechnology, materials science and biomedicine, using drugs or gene technology (CRISPR/Cas9) as a means, employing the intelligent responsive nano-delivery system to achieve the effective regulation of the tumor immune microenvironment, and reduce the recurrence and metastasis of cancer. It provides a new idea for precise, safe and effective therapy of cancer.

1. 云南省“兴滇英才支持计划”—青年人才

2. 云南省科技厅，昆明理工大学“双一流”创建联合专项—重点项目(202301BE070001-001)，2023.12-2026.11，100万，在研，主持

3. 云南省科技厅，基础研究专项—面上项目（202301CF070259），2024.06-2027.05，10万，在研，主持

1. Zebin Yang, Yu Luo, Kaicheng, Liang, Miao Wang, Qigang Wang, Bo Yin*, Hangrong Chen*. Reshaping Tumor Immune Microenvironment Based on Light Activated Nano-Platform for Efficient Cancer Therapy. Adv. Mater., 2022, 34. 2108908.（IF：32.086）
2. Zebin Yang, Yu Luo*, Yanan Hu, Kaicheng Liang, Gao He, Qian Chen, Qigang Wang, Hangrong Chen*. Photothermo-Promoted Nanocatalysis Combined with H2S-Mediated Respiration Inhibition for Efficient Cancer Therapy. Adv. Funct. Mater., 2021, 31. 2007991.（IF：19.924）
3. Zebin Yang, Wenxue Feng, Shixiong Chen, Xiaohong Li, Bo Yin, Hangrong Chen,* A non-drug chemotherapy-like synergizes with gas-/immunotherapy based on cancer cell membrane camouflage-functionalized nanoplatform., Nano Today, 2023, 51. 101912.（IF：17.4）
4. Zebin Yang, Hangrong Chen*. Construction of Multifunctional Nano-Platforms Based on Responsive Gas-Releasing for Tumor Therapeutic Application. Nano Res., 2023, 16. 3924-3938.（IF：10.269）
5. Zebin Yang, Jitao Liu, Jinkun Liu, Xiliang Chen, Tingting Yan, Qinghua Chen*. Investigation on Physicochemical Properties of Graphene Oxide/Nano-Hydroxyapatite Composites and Its Biomedical Applications. J Aust Ceram Soc., 2021, 57, 625-633.
6. Zebin Yang, Hangrong Chen*. The Recent Progress of Inorganic-Based Intelligent Responsive Nanoplatform for Tumor Theranostics. VIEW., 2022, 3. 20220009.
7. Kaicheng Liang, Haitao Sun, Zebin Yang, Huizhu Yu, Jie Shen, Xiaolin Wang, Hangrong Chen*. Breaking the Redox Homeostasis: an Albumin-Based Multifunctional Nanoagent for GSH Depletion-Assisted Chemo-/Chemodynamic Combination Therapy. Adv. Funct. Mater., 2021. 31. 2100355.
8. Miao Wang, Qian Chen*, Dong Xu, Zebin Yang, Jufeng Chen, Yang Zhang*, Hangrong Chen*. Self-cycling redox nanoplatform in synergy with mild magnetothermal and autophagy inhibition for efficient cancer therapy. Nano Today., 2022. 43. 101374.
9. Jingchao Li, Dong Cui, Jiaguo Huang, Shasha He, Zebin Yang, Yan Zhang*, Yu Luo*, Kanyi Pu*. Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy. Angew. Chem. Int. Ed., 2019, 58, 2-10.
10. Jufeng Chen, Fengfeng Xue*, Wenxian Du, Huizhu Yu, Zebin Yang, Qiujing Du, and Hangrong Chen*. An Endogenous H2S-Activated Nanoplatform for Triple Synergistic Therapy of Colorectal Cancer. Nano Lett., 2022, 22, 6156-6165.

1. 陈庆华; 杨泽斌; 刘继涛; 颜廷亭. 一种氧化石墨烯/纳米羟基磷灰石复合硅胶改性多孔支架材料的制备方法, 2020-4-7, 中国, 201810332226.X
2. 陈庆华; 杨泽斌; 颜廷亭; 刘继涛. 一种纳米羟基磷灰石/氧化石墨烯复合材料的制备方法, 2019-7-16, 中国, 201710425341.7